Our group studies the functions of extracellular nucleotides and the receptors via which nucleotides trigger their effects, with a focus on the cell surface, membrane-bound enzymes which hydrolyze these compounds.

We have generated from mice, rabbits and guinea pigs a series of specific antibodies that detect different types of ectonucleotidases from various species including human, mouse, rat, pig and ox.  These antibodies have been tested for immunohistochemistry, immunoblotting as well as flow cytometry.  Some of these antibodies (e.g. human NTPDase2 and -3) specifically inhibit the activity of their target enzyme.  In addition, some of these antibodies can also be used as cell markers. For instance, anti-NTPDase2 may be used to label type I cells in taste buds (which specifically express NTPDase2), and anti-NTPDase1 (= anti-CD39) may be used to label Treg cells (mostly the FoxP3+ subset) which strongly and selectively express CD39/NTPDase1.

These antibodies are available for research collaboration or for purchase.  Contact us to discuss which alternative best suits your purposes.

 

 
 
 
 
 
 
 
 

    

 
 
 
 
 
 
 
 
 
 
 

 

 
 
 
 
 
 
 
anti-NTPDases antibody, anti-CD73 antibody, anti-NTPDase1 antibody, anti-CD39 antibody, anti-NTPDase2 antibody, anti-NTPDase3 antibody, anti-NTPDase8 antibody, anti-ecto-nucleotidase antibody, anti-ENTPD1 antibody, anti-ENTPD2 antibody, anti-ENTPD3 antibody, anti-ENTPD8 antibody, anti-NT5E antibody, anti-ecto-ATPase antibody, anti-nucleoside triphosphate diphosphohydrolase antibody, anti-ATPDase antibody, anti-apyrase antibody, anti-CD39L3 antibody, anti-ecto-5’-nucleotidase antibody, anti-ecto-ADPase antibody, anti-NTPDase 1 antibody, anti-NTPDase-1 antibody,
anti-NTPDase 2 antibody, anti-NTPDase-2 antibody, anti-CD39L1 antibody, anti-NTPDase 3 antibody, anti-NTPDase-3 antibody, anti-HB6 antibody, anti-NTPDase 8 antibody, anti-NTPDase-8 antibody, anti-hATPDase antibody, anti-canalicular ecto-ATPase antibody, anti-ecto-apyrase antibody, anti-ectoADPase antibody, anti-ectoATPase antibody, anti-GDA1 antibody, anti-ATPase antibody,
anti-UTPase antibody, anti-ADPase antibody, anti-UDPase antibody, anti-5’-NT antibody, anti-5-NT antibody, anti-5’NT antibody, anti-5NT antibody, anti-ectonucleotidase antibody, anti-ENTPDs antibody, anti-NTPDases antibodies, anti-CD73 antibodies, anti-NTPDase1 antibodies, anti-CD39 antibodies, anti-NTPDase2 antibodies, anti-NTPDase3 antibodies, anti-NTPDase8 antibodies,
anti-ecto-nucleotidase antibodies, anti-ENTPD1 antibodies, anti-ENTPD2 antibodies, anti-ENTPD3 antibodies, anti-ENTPD8 antibodies, anti-NT5E antibodies, anti-ecto-ATPase antibodies,
anti-nucleoside triphosphate diphosphohydrolase antibodies, anti-ATPDase antibodies, anti-apyrase antibodies, anti-CD39L3 antibodies, anti-ecto-5’-nucleotidase antibodies, anti-ecto-ADPase antibodies, anti-NTPDase 1 antibodies, anti-NTPDase-1 antibodies, anti-NTPDase 2 antibodies, anti-NTPDase-2 antibodies, anti-CD39L1 antibodies, anti-NTPDase 3 antibodies, anti-NTPDase-3 antibodies, anti-HB6 antibodies, anti-NTPDase 8 antibodies, anti-NTPDase-8 antibodies, anti-hATPDase antibodies, anti-canalicular ecto-ATPase antibodies, anti-ecto-apyrase antibodies,
anti-ectoADPase antibodies, anti-ectoATPase antibodies, anti-GDA1 antibodies, anti-ATPase antibodies, anti-UTPase antibodies, anti-ADPase antibodies, anti-UDPase antibodies, anti-5’-NT antibodies, anti-5-NT antibodies, anti-5’NT antibodies, anti-5NT antibodies, anti-ectonucleotidase antibodies, anti-ENTPDs antibodies.